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Utilization of monoclonal antibodies for antigenic characterization of coronaviruses



Utilization of monoclonal antibodies for antigenic characterization of coronaviruses



Annales de Recherches Veterinaires. Annals of Veterinary Research 14(4): 437-444



Hybrid cells secreting monoclonal antibodies against bovine enteric coronavirus (BECV strain G110) were obtained by fusion between SP2/0 myeloma cells and splenocytes of mice hyperimmunized with purified virus. The specificity of 8 of the 12 monoclonal antibodies was established to be anti-GP 105 by immunochemical staining of the viral polypeptides and by immunoprecipitation of radioactive-labelled viral proteins.

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Accession: 001278380

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PMID: 6203462


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