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Can gastrointestinal hormones enhance intestinal absorption?



Can gastrointestinal hormones enhance intestinal absorption?



Surgery 98(3): 430-436



The effect of glucagon and cholecystokinin-octapeptide (CCK-OP) on absorption of substrates was studied in developing and mature small intestine. Developing small intestine was evaluated in a rat foetal intestine transplant model; mature rat small intestine was studied in situ in isolated 10-cm segments of jejunum and ileum. Glucagon, 10 mu g/kg daily, and CCK-OP, 45 mu g/kg daily, were delivered continuously for 14 days through a subcutaneous osmotic pump.

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Accession: 001311948

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PMID: 4035565


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