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Differential activity of maternally and paternally derived chromosomes in mice



Differential activity of maternally and paternally derived chromosomes in mice



Nature, UK 315(6019): 496-498



Mice with paternal or maternal disomy for chromosomes 11 and 13 were produced by intercrossing heterozygotes for the Robertsonian translocation Rb(11.13)4BnR. Mice with disomy 13 appeared normal. Mice with disomy 11 were consistently smaller than their littermates when their chromosomes of pair No. 11 were of maternal origin, but consistently larger than their littermates when their chromosomes 11 were of paternal origin. This was true for both sexes.

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Accession: 001336180

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