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Differential effects of some predominantly antiadrenergic and antidopaminergic neuroleptics on the preovulatory surge of FSH, LH and prolactin in rat



Differential effects of some predominantly antiadrenergic and antidopaminergic neuroleptics on the preovulatory surge of FSH, LH and prolactin in rat



Experimental and Clinical Endocrinology 85(3): 269-275



In experiments performed on rats, single subcutaneous doses of predominantly antiadrenergic neuroleptics significantly depressed the size of the preovulatory serum LH surge. On the contrary, predominantly antidopaminergic compounds elevated the circulating LH concentration and reduced the pituitary LH content. In general, the FSH concentration was not altered significantly by either group of substances. All the neuroleptics increased serum prolactin concentration.

Accession: 001336228

Download citation: RISBibTeXText

PMID: 2864276

DOI: 10.1055/s-0029-1210449



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