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Differential efficacy of levamisole and oxfendazole against resistant male and female Trichostrongylus colubriformis



Differential efficacy of levamisole and oxfendazole against resistant male and female Trichostrongylus colubriformis



Veterinary Record 117(19): 502-503



In lambs naturally infected with strains of Trichostrongylus colubriformis partly resistant to levamisole and oxfendazole, the drugs were more active against male than female worms, and oxfendazole was slightly more active than levamisole. Possible reasons considered for this included sex differences in drug metabolism, mode of attachment to the bowel wall, and mobility.

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Accession: 001336231

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PMID: 4082402



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