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Differential implication of deoxyribonucleic acid methylation in rat prolactin and rat growth hormone gene expressions: a comparison between rat pituitary cell strains



Differential implication of deoxyribonucleic acid methylation in rat prolactin and rat growth hormone gene expressions: a comparison between rat pituitary cell strains



Endocrinology 118(1): 198-206



In order to assess the potential role of DNA methylation in the expression of rat prolactin (rPRL) as compared to rat growth hormone (rGH) gene, the cleavage patterns generated by the isoschizomeric restriction enzymes HpaII and MspI were examined in DNA isolated from rat pituitary cell lines producing either high levels of rPRL (GH3B6) or of rGH (GC) and in a stable variant cell strain which produces minute amounts of both hormones (GH3CDL cells).

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Accession: 001336256

Download citation: RISBibTeXText

PMID: 2416551

DOI: 10.1210/endo-118-1-198



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