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Differential response of lung and liver of juvenile rats to choline deficiency

Differential response of lung and liver of juvenile rats to choline deficiency

Journal of Applied Physiology 59(3): 738-742

The effect of choline deficiency on lung lipids of actively growing male Sprague-Dawley rats was investigated using a washed soyabean protein diet deficient in choline and methionine (lipotrophic). Livers from deprived rats had a significantly increased total lipid content and decreased phosphatidylcholine (PC) content and PC:phosphatidylethanolamine ratio. Although free choline in lung was decreased 40% compared with control values, the PC content of the whole lung homogenate was unchanged.

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Accession: 001336304

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PMID: 3840471

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