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Direct effect of cortisol on androstenedione production by thecal cells from porcine ovarian follicles



Direct effect of cortisol on androstenedione production by thecal cells from porcine ovarian follicles



Animal Reproduction Science 12(1): 39-46



13 Yorkshire pigs, ranging from 8-11 months of age, were slaughtered between days 12 and 20 of the oestrous cycle, after at least 2 normal oestrous cycles. Follicles were dissected from the ovaries and dispersed cells from the theca interna were recovered. A direct effect of glucocorticoids on steroidogenesis was examined by incubating the isolated thecal cells (5 x 105), in triplicate, in 3 ml of TC-199 medium for 3 h with, or without, cortisol (0.92 x 10-7 or 0.92 x 10-6 M).

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Accession: 001336885

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DOI: 10.1016/0378-4320(86)90015-1



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