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Chapter 1,344

Effect of dietary saturated fat and cholesterol mixture on serum cholesterol and development of atherosclerosis in goats

Kaul, P.L.; Prasad, M.C.

Indian Journal of Veterinary Pathology 8: 27-32

1984


Accession: 001343777

Three groups of 6 female goats 3 to 4 months old and initial weight 5 to 6 kg, were given daily 2 g crystalline cholesterol in 45 g of vegetable ghee and 15 g tallow for 2, 4 or 9 months. Hypercholesterolaemia developed in each group. Moderate to pronounced fatty changes were found in the liver of all goats and were directly proportional to the length of feeding period. Varying degrees of intimal sudanophilia (0 to 25% fatty streaks/spots) were present in the aortae of different groups.

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