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Experimental eosinophil accumulation in mice by a thiol protease from metacercariae of Paragonimus westermani



Experimental eosinophil accumulation in mice by a thiol protease from metacercariae of Paragonimus westermani



Japanese Journal of Parasitology 35(1): 63-65



Purified thiol protease from P. westermani (triploid type) metacercariae was injected intraperitoneally at 0.2 ml intact enzyme (0.01 micro g) into normal mice and into mice infected with 20 P. westermani metacercariae. Normal and infected control mice received heat-inactivated enzyme. Eosinophil accumulation in the peritoneal cavity of normal mice was significantly (P < 0.05-0.01) greater than in controls at examination 12 and 18 h after enzyme infection.

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Accession: 001364016

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