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Experimental hepatic amoebiasis in immunosuppressed mice fed orally with cysts of Entamoeba histolytica

Experimental hepatic amoebiasis in immunosuppressed mice fed orally with cysts of Entamoeba histolytica

IRCS Medical Science 13(7/8): 590-591

Azathioprine-immunosuppressed mice were given 4 x 105 cysts of E. histolytica orally. 5 mice were killed on each of days 5, 7, 14 and 21 after infection. Hepatic lesions increased in size with time and were found in all mice from day 7. The caecal wall and caecal contents cultures were positive at day 5; scores increased gradually until day 14 and then declined. 6 mice died during the experiment.

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Accession: 001364035

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