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Experimental hyperlipoproteinaemia and atherosclerosis in miniature pigs: influence of different drugs



Experimental hyperlipoproteinaemia and atherosclerosis in miniature pigs: influence of different drugs



Zeitschrift fur die Gesamte Innere Medizin und ihre Grenzgebiete 41(14): 387-391



Experimental hyperlipoproteinaemia and atherosclerosis were produced in Gottingen miniature pigs by a diet with 11.2% egg yolk and 0.5% cholesterol for 18 months; the hyperlipoproteinaemia was similar to human type IIa according to Fredrickson's classification. Cholesteryl ester-rich atherosclerotic lesions developed mainly in the abdominal aorta and the coronary arteries.

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