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Experimental infection of equine rotavirus in foals



Experimental infection of equine rotavirus in foals



Bulletin of Equine Research Institute (21): 65-71



The HO-5 strain of equine rotavirus (ERV) was isolated from the feces of a foal with acute diarrhea in the horse breeding district in Japan. Two neonatal foals were inoculated orally with equine rotavirus to examine its pathogenicity. The establishment of infection after the inoculation was proved by virus recovery from the intestinal contents and the detection of specific immunofluorescent antigen from the intestine. One foal showed obvious diarrhea. The HO-5 strain of ERV caused diarrhea in neonatal foals and it was an important etiological agent for foal diarrhea which occurred in the horse breeding district. The villous epithelial cells and the cells of villous propria of the jejunum were most important for multiplication of ERV in foals.

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Accession: 001364079

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