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Experimental infection of fetal and newborn Suffolk sheep with scrapie virus

Experimental infection of fetal and newborn Suffolk sheep with scrapie virus

American Journal of Veterinary Research 45(12): 2637-2639

At 76-109 days of gestational age 21 fetuses were inoculated i/m in the neck through the uterine wall, and examined for virus 47-322 days later by mouse inoculation. Scrapie virus was not detected before 254 days of age; only traces of virus were detected in 3 of 7 lambs examined thereafter (2 at 254 days of age and 1 at 322 days of age). Virus was limited to the suprapharyngeal, prescapular, and mesenteric lymph nodes.

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Accession: 001364084

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PMID: 6441491

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