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Experimental infections of human malaria parasites using the old world monkeys

Experimental infections of human malaria parasites using the old world monkeys

Current perspectives in parasitic diseases Proceedings of the Southeast Asian Symposium on parasitology and modern medicine held in Hong Kong, 9-12 December 1983: 213-215

A patent infection of Plasmodium falciparum or P. vivax may be induced in splenectomized juvenile Macaca mulatta, Presbytis francicoisi or M. assamensis if a large volume of infected blood is used and the monkey receives transfusions of healthy human blood. A decreasing parasitaemia may be boosted by a transfusion of healthy human blood. Attempts to adapt the parasite to the monkey host failed after 11 passages which all required the addition of healthy human blood.

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