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Experimental inoculation of cats with canine coronavirus and subsequent challenge with feline infectious peritonitis virus



Experimental inoculation of cats with canine coronavirus and subsequent challenge with feline infectious peritonitis virus



Laboratory Animal Science 34(6): 592-597



Oronasal inoculation of minimal-disease cats with a virulent field isolate of canine coronavirus elicited a neutralizing antibody response that increased steadily over a two-month period, indicating in vivo amplification of the inoculated dose. A heterologous neutralizing antibody response to transmissible gastroenteritis virus was detected three weeks after titres to canine coronavirus were first observed, parallel to the homologous response at about one log10 dilution lower.

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Accession: 001364127

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PMID: 6097763



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