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Experimental leishmaniasis. I. Cutaneous and visceral infections in BALB/c mice



Experimental leishmaniasis. I. Cutaneous and visceral infections in BALB/c mice



Revista Iberica de Parasitologia 44(3): 265-278



Three groups of mice were inoculated with amastigotes of Leishmania mexicana amazonensis, L. donovani or L. donovani infantum. The evolution of cutaneous lesions, the immunological response, and the presence of parasites in blood, liver and spleen were followed up to 14 weeks. All of Leishmania inoculated BALB/c mice were heavily infected, but the speed of evolution of the infection was strongly conditioned by the size of the parasite inoculum.

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