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Experimental production of lesions in canine pulmonary arteries similar to those produced by Dirofilaria immitis infection

Experimental production of lesions in canine pulmonary arteries similar to those produced by Dirofilaria immitis infection

Veterinary Record 116(20): 539-541

Pulmonary arterial disease was produced by the placement of flexible polyvinyl chloride threads (similar in size, shape and flexibility to adult female D. immitis) in the pulmonary arteries of dogs. Several different types of pathological change were apparent, ranging from subendothelial oedema and endothelial loss, mild intimal proliferation and thrombus formation to organized fibrous encasement of the threads in areas where they had become impacted in the lumen of the artery.

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Accession: 001364240

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PMID: 3892873

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