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Experimental studies with goats on the hepatotoxicity of Senecio alkaloids from Senecio vernalis

Experimental studies with goats on the hepatotoxicity of Senecio alkaloids from Senecio vernalis

Praktische Tierarzt 67(4): 322-324

Two goats were each given by rumen fistula 12.1 kg of the dried plant (excluding the root) at the rate of 8.5 kg over 89 days at a constant dosage and 3.6 kg over 18 days at an increasing dosage, then slaughtered. Electron microscopical examination of the livers revealed severe structural damage, particularly to the mitochondria.

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