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Experimental study of fluorosis in lambs

Experimental study of fluorosis in lambs

Annales de Recherches Veterinaires. Annals of Veterinary Research 16(4): 369-377

Two groups of 28 lambs weaned at birth were given increasing daily doses of fluorine, rising by the 8th week to 2 or 4 mg/kg daily. A third group, undosed, served as controls. Fluorine dosing was maintained up to 17 weeks of age, when the animals were slaughtered. Though plasma levels of ionic fluorine rose steadily, and fluoride levels in bones were very high (up to 2.8 g/kg) in dosed groups, there were no abnormal symptoms and no dental nor bone lesions observed.

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Accession: 001364335

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PMID: 4091492

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