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Experimental study of pleuropneumonia caused by Haemophilus (Actinobacillus) pleuropneumoniae in swine. I. Pathogenicity and development of lesions



Experimental study of pleuropneumonia caused by Haemophilus (Actinobacillus) pleuropneumoniae in swine. I. Pathogenicity and development of lesions



Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 36(6): 679-693



A Brazilian isolate of serotype 5 was inoculated into the nose of 16 pigs aged 10-13 weeks. Illness commenced within 6 h. In pigs killed 24 h after infection there were signs of a circulatory disorder in the lungs, with oedematous haemorrhages and exudation of fibrin. The number of mononuclear cells increased between 3 and 5 days after infection. A fibrotic response and necrosis in lung tissue were present between 5 and 27 days.

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