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Experimental therapy of hepatic fibrosis in schistosomiasis japonica. II. Effect of colchicine on hepatic fibrosis



Experimental therapy of hepatic fibrosis in schistosomiasis japonica. II. Effect of colchicine on hepatic fibrosis



Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 2(3): 164-166



28 rabbits, each infected percutaneously with 80 cercariae of Schistosoma japonicum developed pipe-stem fibrosis resembling late human schistosomiasis 4 months later. After a single oral dose of pyquiton 100 mg/kg, colchicine was then given to 9 rabbits orally to treat schistosomal hepatic fibrosis in a dosage of 1 mg daily for 3 months.

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Accession: 001364363

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PMID: 6509741


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