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Experimental vaccination of chickens against avian influenza subtype H5 with an inactivated oil emulsion vaccine



Experimental vaccination of chickens against avian influenza subtype H5 with an inactivated oil emulsion vaccine



Acute virus infections of poultry: 45-51



Doses of 500, 125 or 62.5 mu l of two inactivated influenza vaccines prepared using the virulent A/tern/South Africa/61 (H5N2) strain were injected subcutaneously into five-week-old SPF chicks. HI antibody appeared faster but also waned faster after vaccination with vaccine A, in aqueous solution, than with the oil emulsion based vaccine B. This was associated with a slightly better protection against challenge with the virulent live virus by vaccine A 3 weeks after vaccination.

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Accession: 001364403

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