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Experimental visceral leishmaniasis in the owl monkey

Experimental visceral leishmaniasis in the owl monkey

Veterinary Pathology 23(3): 293-302

Visceral leishmaniasis developed in 8 Aotus trivirgatus after i.v. inoculation with a Khartoum strain (WR378) of Leishmania donovani. 6 monkeys died within 93 days and 2 monkeys recovered. Clinically, signs were weight loss, anaemia and hepatosplenomegaly. Haematological findings included anaemia, granulocytopenia, thrombocytopenia and lymphocytosis. Analysis of serum or plasma revealed hyperbilirubinaemia, azotaemia, hyperglobulinaemia, hypoalbuminaemia and altered haemostasis.

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Accession: 001364408

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PMID: 3727315

DOI: 10.1177/030098588602300310

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