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Extrachromosomal DNA transformation of Caenorhabditis elegans

Extrachromosomal DNA transformation of Caenorhabditis elegans

Molecular and Cellular Biology 5(12): 3484-3496

DNA was introduced into the germ line of C. elegans by microinjection. Approximately 10% of the injected worms gave rise to transformed progeny. Upon injection, supercoiled molecules formed a high molecular weight array predominantly composed of tandem repeats of the injected sequence. Injected linear molecules formed both tandem and inverted repeats as if they had ligated to each other.

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Accession: 001364880

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PMID: 3837845

DOI: 10.1128/mcb.5.12.3484

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