+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Extracts of the ivy plant, Hedera helix, and their anthelminthic activity on liver flukes

Extracts of the ivy plant, Hedera helix, and their anthelminthic activity on liver flukes

Planta Medica: 205-208

Three extracts from English or common ivy, H. helix, were prepared and tested for their antihelminthic activity both in vitro and in vivo. Saponic complex 60% (CS 60), purified saponic complex 90% (CSP 90) and .alpha.-hederin were evaluated in vitro using the trematodes Fasciola hepatica and Dicrocoelium spp. These same extracts were assayed for their effects on Dicrocoelium in naturally infected sheep. After an exposure of 24 h in vitro both Fasciola and Dicrocoelium were killed by .alpha.-hederin at concentrations of 0.005 and 0.001 mg/ml, respectively. When sheep naturally infected with Dicrocoelium were treated p.o. [orally] with CS 60 and CSP 90 the worms were eliminated after 3 doses, one of 500 and two of 800 mg/kg. .alpha.-Hederin was deemed slightly less efficacious at these concentrations. When compared with 2 reference compounds, these extracts show considerable promise. They also appear to be well tolerated by the sheep.

Accession: 001364972

Download citation: RISBibTeXText

PMID: 4034744

DOI: 10.1055/s-2007-969457

Related references

Oldies but goodies: Hedera helix cv. Green Feather, Hedera helix cv. Shamrock, Hedera helix cv. Fleur-de-Lis. Ivy Journal 21: 36-53, 1995

Research of antifungal activity from several active principle extracts from climbing-ivy: Hedera helix L. Annales Pharmaceutiques Francaises 38(6): 545-552, 1980

Effectiveness of plant extracts of Paeonia suffruticosa and Hedera helix against diseases caused by Phytophthora infestans in tomato and Pseudoperonospora cubensis in cucumber. Zeitschrift fur Pflanzenkrankheiten und Pflanzenschutz 111(1): 83-95, 2004

Saponins of the ivy plant, Hedera helix, and their leishmanicidic activity. Planta Medica 57(3): 260-262, 1991

Haemonchus contortus: in vitro and in vivo anthelmintic activity of aqueous and hydro-alcoholic extracts of Hedera helix. Experimental Parasitology 116(4): 340-345, 2007

Hedera helix 'Cross-Stitch' (BF, O), Hedera helix 'Nugget' (V, I): 2005 new registration III - Two new ivies from Cliff Coon Freemont California. Ivy Journal 32: 23-26, 2006

Neurotropic activity of leaf extracts of Hedera colchica (C. Koch) C. Koch and H. helix L. Rastitel' nye Resursy 35(1): 97-103, 1999

Allergic contact dermatitis caused by Hedera helix arborescens and not by Hedera helix L. Contact Dermatitis 66(6): 352-353, 2012

In vitro fasciolicide activity of some plant extracts against newly excysted flukes. Annals of the New York Academy of Sciences 1149: 180-182, 2009

Medusa had two children: Hedera helix 'Chrysaor' (O, V, F) Hedera helix 'Pegasus' (O, F). 2008

Medusa had two children Hedera helix Chrysaor Hedera helix Pegasus. Ivy Journal: 27-30, 2008

Tolerability of dry extracts from ivy (Hedera helix) leaves for children. Zeitschrift fur Phytotherapie 25(4): 179-181, 2004

Toxic and pharmacodynamic actions of ivy extracts hedera helix on the rat. Plantes Medicinales et Phytotherapie 14(4): 221-229, 1980

Expectorant and antitussive effect of Hedera helix and Rhizoma coptidis extracts mixture. Yonsei Medical Journal 56(3): 819-824, 2015

Rapid Determination of α-Hederin and Hederacoside C in Extracts of Hedera helix Leaves Available in the Czech Republic and Poland. Natural Product Communications 10(9): 1529-1531, 2016