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Increased pathogenicity of the avian infectious anaemia agent as a result of simultaneous infection with Marek's disease, bursal disease or reticuloendotheliosis viruses



Increased pathogenicity of the avian infectious anaemia agent as a result of simultaneous infection with Marek's disease, bursal disease or reticuloendotheliosis viruses



Journal of Veterinary Medicine, B Infectious Diseases, Immunology, Food Hygiene, Veterinary Public Health 33(2): 93-116



Strains "Gifu-1" and "Cux-1" of the chick anaemia agent, originally isolated in Japan by N. Yuasa et al., produced atrophy of bone marrow and thymus when inoculated into day-old chicks, but mortality did not exceed 30%. Dual infection with one of the other 3 viruses resulted in more pronounced lesions and higher mortality, probably as a result of immunosuppression.

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