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Isotretinoin for acne: the experience broadens

, : Isotretinoin for acne: the experience broadens. New England Journal of Medicine 313(16): 1013-1014

Side-effects observed when patients with acne are treated by mouth with isotretinoin (13-cis-retinoic acid) are described and discussed and ways in which they may be lessened in incidence and severity are suggested.

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Accession: 001398162

PMID: 2931602

DOI: 10.1056/NEJM198510173131608

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Related references

Almond-Roesler, B.; Blume-Peytavi, U.; Bisson, S.; Krahn, M.; Rohloff, E.; Orfanos, C.E., 1998: Monitoring of isotretinoin therapy by measuring the plasma levels of isotretinoin and 4-oxo-isotretinoin. A useful tool for management of severe acne. Isotretinoin for oral therapy in severe acne conglobata and acne nodulocystica represents a significant achievement; however, the drug exerts several mucocutaneous and systemic adverse effects, besides its teratogenic potency. The aim of this stud...

Dhir, R.; Gehi, N.P.; Agarwal, R.; More, Y.E., 2008: Oral isotretinoin is as effective as a combination of oral isotretinoin and topical anti-acne agents in nodulocystic acne. Due to the late introduction of oral isotretinoin, there is only a single report of the use of this drug from India. To evaluate the efficacy, acceptability and side effects of oral isotretinoin in Indian conditions and to compare the efficacy of...

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