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Papillomas on fish exposed to chlorinated wastewater effluent

Journal of the National Cancer Institute 73(5): 1133-1142
Papillomas on fish exposed to chlorinated wastewater effluent
The presence of carcinogenic and mutagenic chemical(s) in the effluent of a wastewater treatment plant in AL, USA, was indicated by papillomata developing on caged black bullheads (Ictalurus melas), hepatic enzyme induction in exposed fish and Ames test mutagenicity of organic extracts of the wastewater. Although virus-like particles have been reported in papillomata of several other fish species, there was no evidence of the presence of viruses in the black bullhead papillomata.

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Accession: 001424265

PMID: 6593489

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