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Patterns of resistance of inbred mice to Trypanosoma cruzi are determined by parasite strain



Patterns of resistance of inbred mice to Trypanosoma cruzi are determined by parasite strain



Brazilian Journal of Medical and Biological Research 18(4): 499-506



The course of infection with 3 T. cruzi strains (Peruvian, 21SF and Colombian) was studied in 6 inbred strains of mice (A/J, AKR, C3H/He, BALB/c, C57BL/10, DBA/1). As judged by survival, parasitaemia, histopathology and immunological parameters, all 6 mouse strains were highly susceptible to the Peruvian strain, but they displayed a range of susceptibility to the 21SF and Colombian strains.

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Accession: 001425870

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PMID: 3939191


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