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Visualization of Toxoplasma gondii in the cerebrospinal fluid of a child with a malignant astrocytoma

, : Visualization of Toxoplasma gondii in the cerebrospinal fluid of a child with a malignant astrocytoma. Canadian Medical Association Journal 133(3): 213-214

T. gondii trophozoites were observed in stained cerebrospinal fluid (CSF) smears from a 12-year-old boy who was receiving immunosuppression therapy following removal of an astrocytoma. This finding was unexpected because the patient had no history of infection and no clinical features suggestive of toxoplasmosis. Another CSF sample taken 2 weeks later was injected into immunosuppressed mice but failed to produce the disease or antibodies after the 2nd passage.

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Accession: 001507927

PMID: 4016628

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