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Assessment of a general therapeutic protocol for the treatment of acute T-2 toxicosis in swine

Assessment of a general therapeutic protocol for the treatment of acute T-2 toxicosis in swine

Veterinary and Human Toxicology 29(3): 237-239

T-2 toxin, a trichothecene mycotoxin suspected of being used as a chemical warfare agent, was administered i/v to swine at a dose of 3.6 mg/kg body weight (iv LD50 approximately 1.2 mg/kg). Four different therapeutic protocols were assessed for their efficacy in the treatment of the resultant acute T-2 toxicosis. One therapeutic protocol included the combined use of metoclopramide, activated charcoal, magnesium sulphate, dexamethasone sodium phosphate, sodium bicarbonate and normal saline.

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Accession: 001533005

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PMID: 3037764

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