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Assessment of a vaccine against Escherichia coli K99+ diarrhoea in controlled conditions

Assessment of a vaccine against Escherichia coli K99+ diarrhoea in controlled conditions

Revista de Salud Animal 9(1): 61-70

Two immunization schemes with an oil adjuvant E. coli K99+ vaccine were assessed in 172 pregnant cows in five herds. One group received a single dose 45 days before expected calving, and the second group two doses 8 and 4 weeks before calving. There was an increase of blood and colostral antibody levels in vaccinated animals compared to the unvaccinated controls. Blood antibody levels were higher in the calves of vaccinated dams.

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