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Assessment of cytogenetic damage in chagasic children treated with benznidazole



Assessment of cytogenetic damage in chagasic children treated with benznidazole



Mutation Research 206(2): 217-220



Chromosomal aberrations and induction of micronuclei were analyzed from cultures of peripheral lymphocytes in 2 groups of chagasic children, before and after treatment with benznidazole. The median incidence of micronucleated interphase lymphocytes (20 patients) and chromosomal aberrations (10 patients) increased from control values of 5/1000 and 3% to 11.5/1000 and 6%, respectively, at a significance of P = 0.05.

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Accession: 001533035

Download citation: RISBibTeXText

PMID: 3140001

DOI: 10.1016/0165-1218(88)90163-2



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