+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Association of low blood manganese concentrations with epilepsy

Association of low blood manganese concentrations with epilepsy

Neurology 36(12): 1584-1587

A comparison of hospitalized epileptic patients with matched normals showed that the mean whole blood manganese (Mn) concentration of the epileptic population was significantly lower than the mean of the normal population. The whole blood Mn concentration in the epileptics did not correlate either with seizure frequency or with anticonvulsant therapy. It was observed, however, that patients whose epilepsy was a result of trauma had significantly higher blood Mn concentrations than patients whose history was negative for trauma.

(PDF emailed within 1 workday: $29.90)

Accession: 001533382

Download citation: RISBibTeXText

PMID: 3785672

Related references

Manganese and epilepsy roles for both seizures and genes in lowered manganese concentrations in genetically epilepsy prone rats. Society for Neuroscience Abstracts 14(1): 572, 1988

Determination of manganese in cow blood using the flameless atomic absorption spectrophotometry. II. Population investigations into the variability of manganese concentrations in the serum and blood of cows in various production stages. Bulletin of the Veterinary Institute in Puawy 41(2): 115-119, 1997

Brain magnetic resonance imaging and manganese concentrations in red blood cells of smelting workers: search for biomarkers of manganese exposure. Neurotoxicology 28(1): 126-135, 2006

Abnormal aluminum cobalt manganese strontium and zinc concentrations in untreated epilepsy. Epilepsy Research 2(5): 323-330, 1988

Brain manganese concentrations in rats following manganese tetroxide inhalation are unaffected by dietary manganese intake. Neurotoxicology (Little Rock) 23(2): 185-195, July, 2002

Effect of anti epileptic drugs on manganese zinc and copper concentrations in whole blood red blood cells and plasma of epileptics. Clinical Chemistry 25(6): 1111, 1979

Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of manganese citrate as well as manganese and manganese transferrin. Neurotoxicology (Little Rock) 24(1): 3-13, January, 2003

The effect of temperature regime and substrate Mn manganese on growth and manganese concentrations in rice Oryza sativa, tolerance to manganese, cultivar screening. 1982

Position statement on the use of rectal diazepam in epilepsy. Epilepsy Society of Australia, the Child Neurology Study Group, the Australian Association of Neurologists, and the National Epilepsy Association of Australia. Medical Journal of Australia 163(5): 268-269, 1995

Association between lamotrigine concentrations and ABCB1 polymorphisms in patients with epilepsy. Therapeutic Drug Monitoring 34(5): 518-525, 2013

Blood manganese concentrations and intrauterine growth restriction. Reproductive Toxicology 25(2): 219-223, 2008

Whole blood manganese concentrations in dogs with primary hepatitis. Journal of Small Animal Practice 55(5): 241-246, 2015

Manganese concentrations in maternal-infant blood and birth weight. Environmental Science and Pollution Research International 21(9): 6170-6175, 2014

Whole blood manganese concentrations in dogs with congenital portosystemic shunts. Journal of Veterinary Internal Medicine 24(1): 90-96, 2010