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Attenuated strain of Plasmodium berghei obtained by repeated passaging in mice on a vitamin E diet



Attenuated strain of Plasmodium berghei obtained by repeated passaging in mice on a vitamin E diet



Meditsinskaya Parazitologiya i Parazitarnye Bolezni (6): 45-48



Donor mice were given, for 2 weeks before infection with P. berghei, a standard diet (SD) supplemented with vitamin E at 270 micro g/g bwt in vegetable oil. On the 4th day of parasitaemia, 2 recipient groups of mice were infected by donor blood, one group being kept on SD and the other (E) on SD + vitamin E. A 15 day supplementation with vitamin E or oil did not affect the haematocrit or the number of reticulocytes but raised 1.5-fold the level of lactic acid in the blood of mice.

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