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Atypical features in lymphatic filariasis



Atypical features in lymphatic filariasis



Indian Journal of Medical Research 84: 270-274



Examination of 1926 individuals in two villages of Orissa (endemic for Wuchereria bancrofti) revealed nodules in the extremities of 50 subjects. The clinical manifestation of lymphatic filariasis, microfilaraemia and filarial abscesses were observed in 37.2, 15.8 and 11.8 per cent of subjects respectively. The nodules in the extremities appeared along the lymphatic channel probably indicating retrograde movement of adult worms. None of these subjects had received any anti-filarial therapy (DEC) earlier. Nodules removed surgically revealed, on histopathological examination, lymphnode structure with granuloma formation and presence of adult parasite. Seven persons developed multiple bead-like swelling following chemotherapy (DEC). The nodules regressed in size or disappeared when DEC therapy was continued. Similar nodules were also observed in another village of Orissa, endemic for Brugia malayi. These nodules result from granuloma formation in lymphatic filariasis.

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Accession: 001533773

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PMID: 3817927



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