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Azole antifungal agents: emphasis on new triazoles

Azole antifungal agents: emphasis on new triazoles

Antimicrobial Agents and Chemotherapy 32(1): 1-8

The clinical efficacy and toxicity of the azole antifungal agents are discussed, followed by a review of the triazole antifungal agents, in particular fluconazole and itraconazole, focusing on their structure, mechanisms of action, in vitro and in vivo (animal models) antifungal activities and clinical studies.

Accession: 001534346

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PMID: 2831809

DOI: 10.1128/aac.32.1.1

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