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Control of thyroglobulin gene transcription by TSH and cAMP


Hormone and Metabolic Research. Supplement Series 17: 70-73
Control of thyroglobulin gene transcription by TSH and cAMP
The availability of the sequence of the Tg promoter from cattle, rats and humans enabled a comparison to be made from which a general picture of the organisation of the Tg promoter region emerged. Chromatin structure studies identified tissue-specific modifications at the level of DNA-protein interactions. A DNA element was shown to be involved in transcription control by cAMP.


Accession: 001554849

PMID: 2832304



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