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Differentiation of porcine coronavirus from transmissible gastroenteritis virus



Differentiation of porcine coronavirus from transmissible gastroenteritis virus



Veterinary Record 122(4): 86-87



Monoclonal antibodies (MAbs) secreted by mouse hybridomas were tested for their ability to recognise transmissible gastroenteritis virus (TGEV) but not porcine coronavirus (PCV). One MAb, designated 4B1, was identified and its ability to react with TGEV and not PCV-infected cells was confirmed by immunofluorescence. Serum from TGEV-infected pigs was shown to block the attachment of MAb 4B1 to TGEV-infected cell cultures, whereas the serum from PCV-infected pigs did not.

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Accession: 001564812

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PMID: 2451340


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