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Effects of carrageenan on fecal mucinase activity and serum cholesterol level in rats



Effects of carrageenan on fecal mucinase activity and serum cholesterol level in rats



Nutrition Reports International 35(3): 479-486



The role of different levels of carrageenan on fecal mucinase activity and on serum cholesterol level were studied in the laboratory rat. Fiber-free basal diet was mixed with carrageenan at levels of 5, 10 and 15%. Five percent cellulose to the basal diet was used as a comparison. These diets were fed for 28 days to groups of five male Sprague Dawley rats having an average weight of 56.7 g. Mucinase activity was assayed in fresh rat feces. Weight gain of rats fed different dietary groups did not show significant (p > 0.05) difference. Mucinase specific activity was highest in the 15% carrageenan group followed by 10% carrageenan group. Serum cholesterol level were identical in all 5, 10 and 15% carrageenan groups and were significant (p < 0.05) lower than the fiber-free control group. These data suggest that low level of carrageenan may be desirable but excessive intake may not be advisable.

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Accession: 001580021

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