EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Effects of chronic administration of slaframine on production and digestive function in broiler chicks



Effects of chronic administration of slaframine on production and digestive function in broiler chicks



Poultry Science 66(2): 357-362



Slaframine (SF), 1-acetoxy-6-aminooctahydroindolizine a parasympathomimetic with a high affinity for the gastrointestinal tract, was administered by oral intubation daily to 240 broiler chicks at either 0, 8.9, or 17.8 micrograms/kg body weight.75 (BW.75) in saline for 21 days. Throughout the experimental period weight, feed intake, and fecal output were measured. On Day 21 birds were killed, eviscerated, and wet organ weights were obtained. Pancreas and small intestine digesta were homogenized with saline and frozen for analyses of trypsin, chymotrypsin, amylase, and lipase activity as well as total protein. Weight, feed intake and utilization, pancreatic weight, liver weight, and small intestine digesta weight were not affected by SF treatment. Protein content of the digesta decreased 16.6% with the 17.8 micrograms SF/kg BW.75 treatment. Digesta lipase activity was 13.3% (P greater than .05) and specific activity 24% less (P less than or equal to .02) in 17.8 micrograms/kg BW.75 treated birds in comparison with those of controls, and activities decreased in a linear fashion across treatment levels (P less than or equal to .04). Digesta trypsin-specific activity decreased linearly with SF treatment (P less than or equal to .05), averaging 5.5 to 16.9% lower than control treated birds. Pancreatic chymotrypsin-specific activity was not significantly different among treatments. These results suggest that relatively small dosages of SF may affect digestive function of broiler chicks.

(PDF emailed within 0-6 h: $19.90)

Accession: 001580115

Download citation: RISBibTeXText

PMID: 3588504

DOI: 10.3382/ps.0660357



Related references

Effects of chronic administration of slaframine on digestive parameters in broiler chicks. Poultry Science 64(SUPPL 1): 21, 1985

Toxicity of slaframine on broiler chicks and its effects on circulating metabolites and hormones. Poultry Science 65(SUPPL 1): 65, 1986

Tolerance of broiler chicks to slaframine and its effects upon growth hormone glucose and free fatty acids. Poultry Science 64(SUPPL 1): 20-21, 1985

Effects of slaframine on ruminant digestive function: ruminal motility in sheep and cattle. Journal of Animal Science 63(5): 1502-1508, 1986

Effects of slaframine on ruminant digestive function: resting salivary flow and composition in cattle. Journal of Animal Science 62(5): 1404-1411, 1986

Effects of slaframine on ruminant digestive function: liquid turnover rate and fermentation patterns in sheep and cattle. Journal of Animal Science 64(4): 1241-1248, 1987

In ovo EGF administration and its effects on yolk sac absorption and yolk stalk function in posthatch broiler chicks. Poultry Science 78(SUPPL 1): 112, 1999

In ovo peptide YY administration and its effects on the conductive function of the yolk stalk during yolk uptake in broiler chicks. Poultry Science 77(SUPPL 1): 23, 1998

Effect of enzyme supplementation on digestive transit time and volatile fatty acid production in cecum of broiler chicks fed on rye-based diets. Poultry Science 77(SUPPL 1): 73, 1998

Effects of supplementing beta agonist on nutrient metabolism of broiler chicks ii. effects of epinephrine and clenbuterol on energy metabolism and nitrogen retention of broiler chicks. Korean Journal of Animal Nutrition and Feedstuffs 13(5): 253-257, 1989

Effects of different dietary sources of cholesterol protein and fiber on lipid metabolism in broiler chicks 4. effects of feeding vegetable residues extracted with ether or water on serum cholesterol and fecal steroid excretion in broiler chicks. Korean Journal of Animal Science 27(6): 381-385, 1985

Effects of delayed access to feed and different crude protein levels in broiler chicks after hatching 2. Physical development of digestive system. 2005

The effects of administration of various grits on the growth of broiler chicks and their visceral organs. Bulletin of the Hiroshima Agricultural College 4(4): 332-339, 1973

Clinical effects and morphological changes after administration of low doses of ochratoxin A to broiler chicks. Veterinarni Medicina 37(4): 237-242, 1992

Immuno-pathologic effects of oral administration of chlorpyrifos in broiler chicks. Journal of Immunotoxicology 12(1): 16-23, 2015