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Effects of cottonseed cake containing gossypol on antispermatogenesis of male rabbit



Effects of cottonseed cake containing gossypol on antispermatogenesis of male rabbit



Acta Veterinaria et Zootechnica Sinica 18(1): 18-22



Including cottonseed cake (CSC) containing 0.137% free gossypol in the diet of male rabbits caused degeneration of seminiferous epithelium. The degree of degeneration was positively correlated with the amount of CSC and the duration of feeding. Before signs of poisoning appeared antispermatogenesis was shown histologically. There were no histological changes in liver, kidney and spleen. Serum glutamic-pyruvic transaminase increased markedly when the diet contained CSC.

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