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Effects of dietary copper and zinc on serum lipid parameters of young male rats



Effects of dietary copper and zinc on serum lipid parameters of young male rats



Nutrition Reports International 35(3): 551-560



The effects of copper and zinc supplements on serum triglycerides, total cholesterol, and high denstiy lipoprotein (HDL)-cholesterol levels of young rats were studied. In one experiment, copper supplements were 0.56 ppm, 1.68 ppm, and 5.04 ppm, while the levels of zinc were 5 ppm, 10 ppm, and 20 ppm. For a second experiment levels of 5.6 ppm, 16.8 ppm, and 50.4 ppm of copper were used in combination with 50 ppm, 100 ppm, and 200 ppm of zinc. Animals in both experiments were maintained on the respective dietary regimens for six weeks. Increases in dietary zinc were associated with increases in serum triglyceride levels, while serum total cholesterol and HDL-cholesterol levels decreased with increases in dietary copper levels. Dietary zinc/copper ratios had no significant effects on the serum paramenters in this study.

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