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Effects of divergent and antagonistic selection for body weight on sexual maturity in female mice



Effects of divergent and antagonistic selection for body weight on sexual maturity in female mice



Zeitschrift fur Versuchstierkunde 28(4): 187-192



For albino mice (41-96 animals per group), selected for high or low body weight at 8 wk of age (groups 1 and 2), for high or low body weight gains from 3 to 5 wk of age (groups 3 and 4) or subjected to antagonistic selection for high gains from 3 to 5 wk plus low body weight at 8 wk (group 5), body weight at 8 wk averaged 31.5+or-3.4, 21.2+or-3.6, 33.5+or-3.5, 24.1+or-2.4 and 25.7+or-2.2 g resp. vs. 26.6+or-2.0 for 239 unselected controls, age at vaginal opening averaged 33.8+or-0.6, 34.1+or-0.5, 30.0+or-0.5, 32.3+or-0.4 and 29.8+or-0.3 days vs. 31.4+or-0.4, and body weight at vaginal opening 23.4+or-0.4, 17.3+or-0.3, 23.1+or-0.4, 17.4+or-0.3 and 20.3+or-0.2 g vs. 19.1+or-0.3. There were significant regressions of body weight on age at vaginal opening in all groups except group 1 (P<0.05 for groups 3 and 5, P<0.01 in groups 2 and 4 and P<0.001 in controls).

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