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Effects of donor age on urinary chemosignals that influence the timing of first oestrus in young female house mice, Mus domesticus

Effects of donor age on urinary chemosignals that influence the timing of first oestrus in young female house mice, Mus domesticus

Journal of Reproduction and Fertility 83(2): 829-834

The effects of donor age on the effectiveness of puberty-influencing urinary chemosignals in wild house mice was tested in a series of 3 experiments. The chemosignal from male mice that accelerates puberty was present in the urine from about the time of puberty and throughout the normal lifespan, but declined about 1 year of age. Oestrous females released a substance in their urine that accelerates puberty in young females. This substance remained effective from first oestrus until over 1 year of age, although older females were in oestrus less frequently than younger mice. Females that are pregnant or lactating released a puberty-accelerating substance in their urine regardless of age. Production and release of the puberty-delaying chemosignal by grouped females was initiated before puberty and continued throughout the lifespan of the mouse.

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Accession: 001580547

Download citation: RISBibTeXText

PMID: 3411573

DOI: 10.1530/jrf.0.0830829

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