EurekaMag.com logo
+ Site Statistics
References:
54,215,046
Abstracts:
30,230,908
PMIDs:
28,215,208
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Effects of food restriction and restoration on gonadotropin and growth hormone secretion in immature male rats



Effects of food restriction and restoration on gonadotropin and growth hormone secretion in immature male rats



Biology of Reproduction 35(3): 554-561



This experiment concerned the changing patterns in secretion of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and growth hormone (GH) under conditions of food restriction and subsequent catch-up growth. Weanling male rats were given either restricted (4 g food/day) or unrestricted access to food until 60 days of age. At this age, food-restricted rats weighed only 25% as much as rats fed ad libitum. Food restriction resulted in a dramatic decrease in the frequency of LH and GH pulses, and in the amplitude of GH pulses. It also slightly but significantly decreased mean blood levels of FSH (which was not secreted in a pulsatile manner in 60-day-old controls fed ad libitum). When restricted rats were given unrestricted access to food, frequency of LH and GH pulses and mean levels of FSH increased significantly and simultaneously within 2 days in half of the animals. Only an additional 8-10% of their body weight decrement was recovered at this time. After 10 days of food restoration, when restricted rats still weighed 50% less than controls, their secretory patterns of all three hormones were not significantly different from those of controls. Thus, recovery of gonadotropin and GH secretion was relatively rapid. Except for the quantitatively lesser impact of food restriction on FSH secretion, there was no evidence of any priorities in the secretion of the three hormones. Under conditions of rapid catch-up growth, the secretory patterns of LH, FSH, and GH appeared to develop simultaneously.

(PDF emailed within 0-6 h: $19.90)

Accession: 001580935

Download citation: RISBibTeXText

PMID: 3098313

DOI: 10.1095/biolreprod35.3.554



Related references

Effects of morphine and naloxone on gonadotropin, prolactin and growth hormone secretion in the immature male pig. 11th International Congress on Animal Reproduction and Artificial Insemination, University College Dublin, Ireland, June 26-30-1988 Volume 2 Brief communications (Paper 72): 3, 1988

In vivo and in vitro studies on the opioidergic control of the secretion of gonadotropin releasing hormone and luteinizing hormone in sexually immature and adult male rats. Neuroendocrinology 53(6): 579-588, 1991

Modulation of gonadotropin secretion at the pituitary level by testosterone in gonadotropin-releasing hormone-treated male rats during food deprivation. Biology of Reproduction 52(4): 808-813, 1995

Effects of central and peripheral type benzodiazepine ligands on growth hormone and gonadotropin secretion in male rats. Pharmacology & Toxicology 71(1): 75-80, 1992

Long-term effects of early postnatal food restriction on growth hormone secretion in rats. Jpen. Journal of Parenteral and Enteral Nutrition 27(4): 260-267, 2003

Danazol effects on gonadotropin basal levels and pituitary responsiveness to luteinizing hormone releasing hormone in immature male rats. Contraception 17(1): 61-70, 1978

Effects of luteinizing hormone follicle stimulating hormone releasing hormone and sex steroids on gonadotropin secretion in normal male rats. Experientia (Basel) 29(6): 748, 1973

Effects of luteinizing hormone releasing hormone and sex steroids on gonadotropin secretion in normal male rats. Acta Endocrinologica Supplementum 177: 261, 1973

Effects of continuous inhibin administration on gonadotropin secretion and subunit gene expression in immature and adult male rats. Biology of Reproduction 55(6): 1377-1382, 1996

The role of growth hormone in the control of gonadotropin secretion in adult male rats. Endocrinology 139(3): 1067-1074, 1998

Effects of age and endogenously secreted human growth hormone on the regulation of gonadotropin secretion in female and male transgenic mice expressing the human growth hormone gene. Endocrinology 132(4): 1482-1488, 1993

Dexamethasone suppresses gonadotropin-releasing hormone (GnRH) secretion and has direct pituitary effects in male rats: differential regulation of GnRH receptor and gonadotropin responses to GnRH. Endocrinology 122(6): 2873-2880, 1988

Modulation of basal and gonadotropin releasing factor stimulated growth hormone secretion by melatonin and vice versa in male rats. Neuroendocrinology Letters 7(3): 148, 1985

Early and temporary quantitative food restriction of broiler chickens. 2. Effects on allometric growth and growth hormone secretion. British Poultry Science 41(3): 355-362, 2000

The regulation of gonadotropin secretion in immature ethanol treated male rats. Journal of Andrology 3(4): 248-255, 1982