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Hereditary and acquired complement deficiencies in animals and man


, : Hereditary and acquired complement deficiencies in animals and man. Progress in Allergy 39: 1-404

This multi-author book contains comprehensive reviews of the complement system and deficiencies of complement components.

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Accession: 001607738

PMID: 3562458

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Matsubara, Y.; Murata, M.; Moriki, T.; Yokoyama, K.; Watanabe, N.; Nakajima, H.; Handa, M.; Kawano, K.; Aoki, N.; Yoshino, H.; Ikeda, Y., 2002: A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibalpha. Platelet glycoprotein (GP) Ib/IX/V complex mediates high-shear dependent platelet activation through an interaction with the von Willebrand factor (vWF). All four subunits of the complex have a structural motif, the leucine-rich repeat (LRR) seque...

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