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Hereditary juvenile neuronal muscular atrophy in Swedish Lapland dogs - the present position


, : Hereditary juvenile neuronal muscular atrophy in Swedish Lapland dogs - the present position. Svensk Veterinartidning 38(15): 162-164

The disease, which has an autosomal recessive mode of inheritance, appeared in Swedish Lapland dogs in the late 1960s, and a test mating programme began in 1973 in an attempt to eradicate the disorder. At the end of 1983, 260 and 297 non-carriers had been identified by virtue of siring at least 11 normal pups when mated with a known heterozygote.

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Related references

Sandefeldt, E.; Cummings, J.F.; de Lahunta, A.; Björck, G.; Krook, L.P., 1976: Animal model of human disease. Infantile spinal muscular atrophy, Werdnig-Hoffman disease. Animal model: Hereditary neuronal abiotrophy in Swedish Lapland dogs. American Journal of Pathology 82(3): 649-652

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