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Heterocyclic sulphur compounds with antifungal properties: a study of the in vitro activity of various 5-aryl-1,2 dithiole-3-thiones on various fungi pathogenic to man


Annales Pharmaceutiques Francaises 44(2): 157-162
Heterocyclic sulphur compounds with antifungal properties: a study of the in vitro activity of various 5-aryl-1,2 dithiole-3-thiones on various fungi pathogenic to man
The orthophenyl substituted derivatives (OCH3CH3Cl) were found to inhibit the growth of dermatophytes (Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes) at min. inhibitory concn (MICs) of between 50 micro g/ml and 100 micro g/ml. Compounds with a pyridine ring instead of a phenyl ring exhibited moderate activity against Candida albicans.


Accession: 001607915



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